30/03/2020 11:11:24 |
0 binh luận
Diagnostic performance of stress perfusion cardiovascular magnetic resonance for detection of Ischemia Heart Disease SUMMARY: Objective: Evaluation of the diagnostic of stress perfusion cardiovascular magnetic resonance for the diagnosis of significant obstructive coronary artery disease in comparison to invasive coronary angiography. Material and Methods: 36 patients with suspected ischemic heart disease/ 25 males (69.4%) with mean age: 65.53 ± 10.48 year underwent 1.5 Tesla CMR including cine, short axis to evaluate EF, EDV, ESV, stress PERF (adenosine 140 μg/min/kg), rest PERF (SSFP, 3 short axis, 1 saturation prepulse per slice) and LGE (3D inversion recovery technique) using Gd-BOPTA. Images were analyzed visually. Stenosis >50% in invasive angiography was considered significant. Results: Mean study time was: 45.44 ± 9.18 minutes, EF: 45.06 ± 15.66%, Hypokinesia: 44.4%, Akinesia: 27.8%. The overall patient-based analysis demonstrated a high sensitivity, specificity and PPV for perfusion was 93.3%; 83.3%; 96.6% and moderate NPV 71.4%. A good relation (p<0.01) between deficit perfusion state correlation with coronary stenosis of LAD, RCA, LCx . Conclusion: Stress perfusion CMR with Adenosine is highly sensitive and specificity for detection of coronary artery disease. Keywords: Cardiac Magnetic Resonace (CMR), diagnose, coronary artery disease, ischemia heart disease (IHD), coronary artery, perfusion, Adenosine.