Assessment of left ventricular dyssynchrony by SPECT myocardial perfusion imaging in post myocardial infartion patients SUMMARY Objective: to evaluate left ventricular synchrony parameters using gated myocardial perfusion single photon emission computed tomography (GSPECT) in post myocardial infarction (MI) patients. Subject and methods: a cross - sectional study was conducted on 34 subjects without cardiovascular disease and 104 post-MI patients. Results : left ventricular dyssynchrony parameters including PSD and HBW were 48.7 ± 19.49 and 154.95 ± 71.97 in post-MI group compared to 17.5 ± 7.24 and 53.9 ± 15.14 respectively in control group (p<0.01). 77% and 81% of post-MI patients had increased PSD and HBW with left ventricular dyssynchrony. PSD and HBW has increased significantly in post-MI patients with NYHA III-V, low EF compared to NYHA I-II patient group without left ventricular dysfunction. Conclusion : left ventricular dyssynchrony parameters were commonly detected by gated SPECT in post-MI patients. PSD and HBW increased significantly in post-MI patients and had relationships to NYHA and left ventricular dysfunction. Keyword: myocardial perfusion imaging, left ventricular dyssynchrony, myocardial infarction.

Initial evaluation the result of treatment for lung metastasis by radio frequency ablation in vietduc hospital SUMMARY Purpose : We aimed to evaluate the effectiveness and the complicationsof radiofrequency (RF) ablation of metastatic lung tumors Methods: Eight patients with lung metastatic underwent computed tomography-guided percutaneous RF ablation between May 2016 and August 2018. A total of 11 tumors (8 metastatic from hepato cellular carcinoma, 2 metastatic from chorio and 1 metastatic from colon cancer) were treated with RF ablation (9 sessions). Tumor diameter ranged from 0.9 to 1.9 cm (median 1.26cm). Effectiveness of treatment and complications were analyzed. Results :Success rate was 100 % with only one session, local tumor progression hasn’t occurred in 11 tumors. Complications occurred in 5 sessions (55.5%). Chest pain occurred in 2 sessions andpneumothorax occurred in 3 sessions with one requiring image-guided percutaneous chest tube drainage. \ Conclusion: RF ablation is a safe and effective treatment for selected patients with metastatic lung tumors. Key words : radio frequency ablation, pulmonary metastasis, lung cancer.

Evaluation of changes in semen, sex hormones after intervention in varicocele SUMMARY Purpose: Evaluating the technical feasibility an semen quality after intervention of varicocele. Subjects and research methods: Among 101 patients treated with varicocele emboization during 2 years. With 50 patients were followed up before and after embolization 6 months by the size of the vein, testes, and semen index including concentration, morphology, mobility, hormonal (including Testosterol, LH, FSH). Technical details, reasons for the failure of the procedure are noted. Using pairing comparison algorithm before and after treatment. Results: 100% technical success. The indicators of spermatozoa including sperm concentration, morphology and mobility were improved with the reliability of 95%, especially sperm motility index, PR - sperm rised signigicantly with Z = 4,1 ± 1,51 (before and after treatment). The index of testosterol hormones increased significantly after treatment with Z = 1.81 ± 1.32, LH and TSH hormonal indexes did not change significantly. Conclusion : Intervention of varicococele has been shown to be effective in improving semen and testosterone index. Key word : Intervention of varicocele, Sperm, testosterone index.

Relationships between BRAFV600E mutation, clinicopathologic factors and 18F-FDG avidity in radioiodine-refractory differentiated thyroid carcinoma patients SUMMARY Objectives: The BRAFV600E mutation is one of the prognostic factors in thyroid carcinoma related to GLUT-1 expression which increases 18F-FDG uptake. In this study, we investigated the relationship between BRAFV600E mutation, clinicopathologic factors and 18F-fluoro-2-deoxyglucose (18F-FDG) avidity in radioiodine-refractory differentiated thyroid carcinoma. Methods : Total 46 radioiodine-refractory DTC patients who underwent BRAFV600E analysis from the biopsy and 18F-FDG positron emission tomography/computed tomography from 2011 to 2018. Semi-quantitative analysis of highest hypermetabolic lesion was accessed by automated polygonal regions of interest (ROIs) drawing on attenuation-corrected PET images the Workstation AW4.7(GE). The relationship between BRAF mutation, clinicopathologic factors, and 18F-fluoro-2-deoxyglucose (18F-FDG) avidity was investigated. Results : Patients with the BRAFV600E mutation present higher 18F-FDG uptake (median of SUVmax: 7,11) than those without mutation (median of SUVmax: 4,91) but the difference is not statisticcal significance (p=0,236). The tumor size (p = 0.006) and distant metastases (0,03) were significantly associated with 18F-FDG uptake in univariate analysis. Aggressive histopathologic type of DTC is only the factor (p = 0.01) related to FDG uptake significantly (p = 0.01) in both univariate and multivariate analysis. Conclusion : The aggressive and classic type of DTC were the factors significantly related to 18F-FDG avidity in both univariate and multivariate analysis. The effect BRAFV600E of mutation on glucose metabolism in radio iodine refractory patients needs further study in larger groups of patients. Key words : 18F-fluorodeoxyglucose, Positron-emission tomography, BRAFV600E mutation, histopathologic type, radioiodine refractory.

The relationships between suvmax and morphologic features of bone metastatic lesions on 99mtc-mdp spect/ct in known cancer patients SUMMARY The aim of our study was to evaluate the relationships between SUVmax and morphologic features of bone metastasis on 99mTc-MDP SPECT/CT in known cancer patients. Materials and Methods: This prospective study enrolled 90 known cancer patients (32 women and 58 men patients with aged average of 61.6 ± 10.4) underwent 99mTc-MDP SPECT/CT scans from February 2018 to February 2019 at Nuclear Medicine Department, 108 central military hospital. Bone metastatic lesions were classified based on morphologic features on CT. The standadized uptake values (SUVmax) were measured at each morphologic features of bone metastasis and determining the relationships between SUVmax and those lesions in different primary cancer diseases. Results : The total of 264 lesions were found in 90 patients. Of which, 29% was osteolytic, 25% was osteoblastic, 23% was mixed and 23% was unclassified lesions on CT. SUVmax values at osteolytic lesions were significantly lower than other types of lesions (p<0.05). SUVmax values of bone lesions in thyroid cancer, liver cancer patients were lower compared to those in prostate cancer and lung cancer patients. This difference was statistically significant (p<0.05). Conclusions: The morphologic features of bone metastatic lesions on CT were found to be in correlation to metabolic bone changes on 99mTc- MDP SPECT/CT imaging. Keywords: SPECT/CT, bone metastasis, SUVmax

Applicaton of lung low dose scan on msct system Bach Mai radiology center, 2018 SUMMARY Summary: Target (main point, purpose of this reseach); Standard dose CT ( SDCT) has been one of the most valuable techniques in term of diagnosing lung diseases. But it also have side effect that huge radiation dose is absorbed to patients body; In order to reduce this side effect is low dose CT scan (LDCT); LDCT help patients reduce radiation dose absorb to their body. Subject: 300 patients with SDCT scan: 120 kV, 87.5 - 140mAs; 300 patients with LDCT scan: 100 kV, 35-52.5 mAs. Hitachi CT 128 slices System. Evaluate image quality, dose information( CTDI vol, DLP, Effective dose) of two group Result : Effective dose: SDCT: 120kV, 87,5-140mAs and LDCT: 100kV, 35-52.5mAs => LDCT reduce 2,5 time compare to SDCT; Absorded dose CTDI vol of LDCT: 2,3 + - 0.5 mAs à reduce by 60% compare to SDCT (P<0,001); DLP of LDCT: 80+- 159.99 mGy.cm à reduce by 65% compare to SDCT ( P<0.001). Quality of image: both are the same and enough for diagnose Conclusion: Absorbed dose and effective dose of LDCT are reduce significantly. The image quality are still have enough value for diagnose. Key words : CT reduces the dose of rays; Low-dose chest CT; Pulmonary nodule; Risk factors for lung nodules.

The relationship between clinical characteristics, semen test with color Doppler ultrasound in adult varicocele patient under 40 years old SUMMARY Purpose: Determine the relationship between clinical characteristics and semen test with color Doppler ultrasound in adult varicocele patientsunder 40 years old. Methods: A total of 56 patients with clinical diagnosis of varicocele were clinically graded according to Dubin and Amelar [1], calculated body mass index (BMI), did semen test and color Doppler ultrasound scrotum. Then they were calculated according to Chiou's scoring system [2] to determine varicocele. To assess the relationship we use Chi-Square test, two qualitative variables were identified as relevant when the p-value<0.05. Result s: There was arelationship between diagnosis of Doppler ultrasound according to Chiou with clinical varicocele (p<0.05). There was no relationship between BMI and diagnosis of varicose veins Doppler (p> 0.05). There was a relationship between the semen test and the diagnosis of varicocele on color Doppler ultrasound (p<0.05). Conclusion : Our study has shown a relationship between color Doppler ultrasound diagnosis based on Chiou's scoring system with clinical grade and semen test in adult varicose veins under 40 years old. Keywords : Varicocele, Color Doppler ultrasound, male infertility.

Single coronary artery: classification and clinical significance SUMMARY Objectives: To evaluate ratio and classification single coronary artery in the MSCT cardiac. Material and Methods: Prospective study of 9,868 patients who had scanner MSCT cardiac in Ha Noi Heart Hospital from February, 2015 to September, 2017. Results: The study included 9,868 patients, 43 patients (0,44%) had single coronary artery. 11/43 patients (25,6%) had single coronary artery were isolated. 32/43 patients (74,4%) associated had congenital heart diseases other: 7 patients had Fallot 4, 3 patients had truncus arteriosus, 2 patients had pulmonary atresia, 1 patient had double outlet right ventricle, 1 patient had double discordance and 18 patients had complex congenital heart diseases. Included 43 patients had single coronary artery: 16/43 patients ( 37%) in the type R, 25/43 patients (58%) in the type L and 2/43 patients (5%) not in the current classification who had singler coronary artery high takeoff from truncus brachiocephalic artery. Type L I was 5%, type L II – A: 21%, type L II – B: 18%, type L II – P: 14%, type R II – A: 18%, type R II – B: 12%, type R II – P: 5% and type R III: 2%. Conclusions: Singler coronary artery is a rare congenital anomaly. MDCT cardiac is a non-invasive technique, reliable, that provides accurate information about coronary artery anatomy well as other complex congenital heart diseases. Single coronary artery is a great challenge for surgery to repair the entire congenital heart disease that accompanies it. Keyword : Coronary artery anomalies, Single coronary artery, Coronary angiography, Congenital heart, Surgery congenital heart.