SUMMARY A cross-sectional descriptive study was conducted on 1436 patients after SARS-CoV-2 infection who visited MEDLATEC medical facilities from March 1, 2022 to March 31, 2022. The results showed that 39% were male and 61% female, with a mean age of 39 and the majority of patients in the working age range from 18-60 years old. 74% of patients infected with SARS-CoV-2 have clinical symptoms, of which cough is the most common symptom, followed by chest pain and shortness of breath. The group of patients with a healthy history accounted for 76% of cases; the remaining group of underlying diseases with hypertension accounted for the most, followed by the group with chronic lung disease. Up to 49% of patients have suspected COVID-related lung lesion; with the most important lesions being interstitial thickening and most of them being mild according to the CT-score scale. Keywords: clinical characteristics, CT scanner, SARS-CoV-2

SUMMARY Background: We aimed to investigate the performance of a chest X-ray (CXR) scoring scale of lung injury in prediction of death among patients with COVID-19 admitted at Vinmec Central Park hospital (HCM City, VN) during the peak epidemic in 2021. Method: Retrospective design; X-ray images and clinical data were collected from all hospitalized patients with SARS-CoV-2 PCR positive from July to September 2021. Three radiologists independently assessed the CXR score at admission which consists of measuring both severity and extent of lung injuries on four lung quadrants (scale o to 24). Association between CXR and mortality risk was estimated using a survival regression with log-log distribution. Result: The study included 219 patients (mortality rate = 28). There was a high consensus for CXR scoring among 3 radiologists (κ = 0.90; CI95%: 0.89-0.92). PCA analysis revealed that CXR has a similar role as CRP score for predicting risk of mortality. CXR score was the strongest predictor of mortality (tdAUC 0.85 CI95% 0.69–1) within the first 3 weeks after admission, compared with other conventional clinical features. After adjusting for the patient’s age, there was a significant effect of increased CXR score on mortality risk (HR = 1.15, CI95%:1.04-1.27, p=0.009). At a critical threshold of 16 points, the CXR score allows for predicting inhospital mortality with good sensitivity (0.82; CI95%: 0.78 to 0.87) and specificity (0.89; CI95%: 0.88 to 0.90). Conclusion: The day-one CXR score is an independent and effective predictor of the risk of death in COVID-19 and could be used to identify high-risk patients in countries like Vietnam where CXR is more readily available than CT scans. Keywords: COVID-19, Chest X-ray, Lung injury score, Mortality prediction

SUMMARY Purpose: to assess left atrial appendage morphology by multidetector computed tomography in atrial fibrillation (AF) patients for catheter ablation Materials and Methods: This retrospective and cross-sectional study included 45 patients diagnosed with AF and treated by catheter ablation and 45 patients without AF undergoing multi-detector computed tomography in E hospital from 1/2020 to 7/2022 Results: The mean age 56.16 ± 11.83, median of left atrium volume in the AF group was 118.13 (96 - 145.56) ml > the control group 72.88 (60.53 - 95.74) ml, (p < 0.001). The most common left atrium morphology in both groups is "cactus" with 46.67% in the AF group and 33.33% in the control group, the middle left atrial appendage orifice was the most common in the AF group (53,33%), while in the control group, the lower left atrial appendage orifice was the most common (44.44%), the length of the left atrial appendage in the AF group was 43.15 ± 8.11 mm, the control group was 44.29 ± 9.76 mm. There is a positive correlation with the mean level between left atrial appendage length and left atrial volume (r = 0.573, p < 0.001). Conclusion: The most common left atrium morphology in both groups is "cactus". There is a positive correlation with the mean level between left atrial appendage length and left atrial volume. Keywords: atrial fibrillation, catheter ablation, left atrial, left atrial appendage, multi-detector computed tomography

SUMMARY Purpose: to evaluate and analyze the ratio of position, depth and length of the coronary myocardial bridge, the status of pre-myocardial atherosclerosis and the degree of vascular stenosis during systole by multislice-computed tomography (MSCT) images series. Material and method : Computed tomography scan for 175 patients using a 256-row MSCT machine at Hanoi Friendship Hospital between July 2021 and August 2022. Select the best quality images in systole and diastole. Measure the length and thickness of the bridge. For each myocardial bridge segment, assess for the presence of anterior atherosclerotic plaque no more than 2 cm in length of the artery. Assess the degree of vascular stenosis during systole caused by the myocardial bridge. Result: Most of the myocardial bridges were located in the anterior interventricular artery (LAD) (98.3%). The average values of the length and thickness of the bridge are 23.1 ± 10.5mm and 1.0 ± 1.0mm. Atherosclerosis was detected in 77 cases (accounting for 43%). The average degree of tunneling artery stenosis was 23.0% systolic. Conclusion: MSCT 256 series has a high value in detecting bridges, determining the location, there by measuring the length, the thickness of the pons, the status of anterior atherosclerotic plaques as well as the degree of narrowing of the vessel lumen systole of the musculature. Keywords: myocardial bridge, coronary artery, multislice computed tomography.

SUMMARY Purpose: The study aimed to initial evaluate the value of interim PET/ CT after 2 cycles of ABVD chemotherapy in Hodgkin lymphoma patients. Material and Methods: The study was carried out retrospective and prospective descriptive study on 56 patients at Tan Trieu K Hospital from March 2020 to June 2022. Patients were examined clinically, paraclinically, had a CT scan or PET/CT film before treatment, then received ABVD chemotherapy, after 2 cycles of being taken and evaluated Interim PET/CT, and continued treatment based on the results. Result of iPET/CT leads to continue or change of regimen continued treatment or change of regimen and follow-up. Results: In a total of 56 patients, male/female ratio: 1/1.6, mean age 30±12.6 (youngest age 7 years old, oldest age 67 years old). 35/56 patients (62.5%) had CT scan and 21/56 patients (37.5%) had background PET/CT scan before treatment. 30.4% had 2 lymph node sites and 28.6 patients had 3 lymph node sites on the body, lymph nodes above the diaphragm 67.9% and lymph nodes both above and below the diaphragm 12,5%. 49 patients had lymph node lesions, short axis size of lymph nodes maximum 27.10±8.3 mm. Lesion to the mediastinum in 15/58 patients (25.8%), spleen in 5 patients. Patients with early stage I-II accounted for 82.1%, advanced stage III-IV accounted for 17.9%. After 2 cycles of ABVD chemotherapy, the response rate on PET/CT was iPET/CT2 (-) 43/56 patients (76.8%, of which Deuville score 1 point 93%) and iPET/CT2 (+) in 13/56 patients (23.3%). The prognostic index of IPS low-risk group (0-2) complete metabolic response was 86.4%. In the high-risk group IPS (4-7) partial metabolic response and complete metabolic response was 54.5% according to Lugano classification. Conclusion: Interim PET/CT has an important role in providing prognostic information in the treatment of ABVD chemotherapy in Hodgkin Lymphoma patients, reducing the toxicity of chemotherapy and determining the next treatment modalities. Keywords: lymphoma Hodgkin, interim PET/CT.

SUMMARY Prostate cancer (PC) is an emerging male health problem in recent years due to new development in diagnostic and treatment modalities that help improve disease prognostic, especially in Eastern countries where PC incidence is high. According to GLOBOCAN 2020, number of new cases of PC reached 1,414,259 while number of deaths was 375,304 cases. In terms of deaths due to cancer in male population, prostate cancer ranks two just after lung cancer. Together with the traditional trio of rectal exam, Prostate-Specific Antigen (PSA) and transrectal ultrasound, emerging imaging modalities such as elastography ultrasound, multimodality magnetic resonance imaging not only helped physicians better detecting malignant lesions at supra early stage but also guided biopsy for pathological assessment. These new innovations led to preference of target-biopsy with lower rate of re-biopsy and complications comparing to systemic biopsy technique

SUMMARY Placenta acrreta spectrum is a condition in which the placenta partially or completely invades and cannot be separated from the uterus muscle. Placenta previa is a condition in which the placenta partially or completely covers the cervix. Both phenomena increase the risk of postpartum haemorrhage, hemostasis disorders, and threaten the life of the mother and the fetus. Combine of the two phenomena increase blood loss in cesarean delivery as well as postpartum period, and is a great challenge required multidisciplinary for successful management. Prophylactic endovascular intervention is a minimally invasive treatment method, which plays an important role in prevent haemorrhage in the management of placenta accreta spectrum. This report describes a case of placenta percreta combine with placenta previa, which received prophylactic endovascular intervention using balloon occlusion of internal illiacs and uterine arteries embolization and underwent a cesarean delivery at 36 weeks. The patient had a successful delivery and preserved the uterus after surgery. Key word : Placenta acrreta spectrum, prophylatic balloon occlusion, uterine artery embolization

SUMMARY Sarcoma is a general term for a type of cancer found in the connective tissue cells (the cells of the mesenchyme). There are many types of sarcoma because connective tissue cells are present everywhere in the body (bone, cartilage, blood vessels ...) but this type of cancer is divided into 2 main groups, bone sarcoma, and soft tissue sarcoma. Rhabdomyosarcoma (RMS) belongs to the group of soft tissue sarcoma of skeletal muscle, is a common malignancy, and is one of the leading causes of cancer death in children. Alveolar rhabdomyosarcoma (ARMS) is a subtype of RMS that is extremely rare in adults. We present a pediatric case of ARMS, primary in the butt area with pulmonary metastases, confirmed by histopathology and immunohistochemistry. Reported data and literature review will help physicians have a better diagnostic approach when encountering similar cases. Keyword: Rhabdomyosarcoma; alveolar rhabdomyosarcoma, soft tissue tumor lung metastasis.