SUMMARY Purpose: To compare the ultrasound results of thyroid nodules in the application of EU-TIRADS, K-TIRADS, ACR-TIRADS systems with post-operative histological results. To compare diagnostic values of the three TIRADS systems. Material and methods: This is a cross-sectional study with convenient sampling. We recruited thyroid nodules that were performed pre-operative ultrasound (applied EU-TIRADS, K-TIRADS, ACRTIRADS systems) and removal surgery in Hue University of Medicine and Pharmacy Hospital between September 2019 and July 2020. Results: 138 thyroid nodules of 122 patients were enrolled. The malignancy rate was 22.5%. The majority of the lesions were classified as EU-TIRADS 3 (47.8%), K-TIRADS 3 (47.8%) và ACR-TIRADS 2 (38.4%.). The AUC of the EU-TIRADS, K-TIRADS và ACR-TIRADS systems were 0.957, 0.951 and 0.956, respectively. Among the three systems, EU-TIRADS had the highest sensitivity (Se) and negative predictive value (NPV) (100%) while its specificity (Sp), positive predictive value (PPV) and accuracy (Acc) for malignancy were lowest. K-TIRADS showed the best Sp, PPV and Ac (97.2%; 89.7% and 94.2%, respectively) and the lowest other values. Conclusion: The ability to distinguish between the malignant thyroid nodules and the benign ones of the three TIRADS systems was at a very good level. EU-TIRADS showed the most effective diagnostic performance in Se and NPV, while K-TIRADS yielded the best Sp, PPV and Acc. Key words: thyroid nodules, diagnostic values, EU-TIRADS, K-TIRADS, ACR-TIRADS.

Covid-19 (coronavirus disease 19) đang là một trong những thách thức lớn nhất cho thế giới trong thời điểm hiện tại. Những tác động của coronavirus (SARS-CoV-2) không chỉ đơn thuần lên sức khỏe, mà còn ảnh hưởng nghiêm trọng đến kinh tế và cuộc sống của người dân trên toàn cầu. Một vài nước đã thông báo rằng họ đang trải phải qua một trong những tình huống tồi tệ nhất trong hơn 100 năm vừa qua.

SUMMARY Objective: To determine the value of ultrasound in the diagnosis of thyroid cancer. Subjects and methods: A cross-sectional descriptive study on 98 patients with thyroid nodules who came for treatment at the Military Institute of Medical Radiology and Oncology, from April 2020 to March 2021. Results: The size of malignant nodules was mainly less than 2cm. Thyroid cancer lesions were mainly characterized by highly hypoechoic on ultrasound (61.19%). Thyroid cancer nodules had taller-than-wide feature (Sensitivity: 76.12%; specificity: 86.96%; positive predictive value: 89.47%; negative predictive value: 71.43%; accuracy: 80.53%.); irregular border feature (sensitivity: 98.51%; specificity: 86.96%; positive predictive value: 91.67%; negative predictive value: 97.56%; accuracy: 93.81%); microcalcification characteristics (sensitivity: 73.13%; specificity: 91.30%; positive predictive value: 92.45%; negative predictive value: 70.00%; accuracy: 80,53%). TIRADS value in thyroid cancer diagnosis with sensitivity: 94.03%; specificity: 86.96%; positive predictive value: 91.30%; negative predictive value: 90.91%; Accuracy: 91.15%. Conclusion: The features of hypoechoic nodules, taller-than-wide shape, irregular border, microcalcification characteristics, and TIRADS 4, TIRADS 5 scores had high prognostic value for thyroid cancer. Keywords: Ultrasound, thyroid cancer.

SUMMARY Objectives: Describe the characteristics of ultrasound images, computed tomography, angiography and results of chemoembolization in patients with HCC under 40 years old at the Radiology Center of Bach Mai Hospital. Methods: A cross-sectional study was carried out on 25 patients with a confirmed HCC who treated chemoembolization at the Radiology Center - Bach Mai Hospital from August 2018 to August 2021. Results: On 2-dimensional ultrasound, the majority of HCC tumors had hypoechoic and mixed sound images (72%) and increased angiogenesis on color Doppler ultrasound, reaching 68.0%. On computed tomography images, tumor density decreased 64% and increased angiogenesis 68.0%. Tumors of HCC have increased angiogenesis on angiography, reaching 92%. After treatment AFP tends to decrease in the first 6 months, then increase in the 9th month. Bilirubin tends to decrease in the first 3 months, then increase at 6 and 9 months. Tumor size tends to decrease at 1, 3 and increase at 6, 9 months. Median survival was 13 months with interquartile range [5.5 ÷ 22], the longest survival time with continued follow-up was 57 months. Conclusion: Chemoembolization therapy is effective in reducing tumor size, bilirubin, AFP and prolonging survival time for patients under 40 years old with HCC. Keywords: chemoembolization therapy, hepatocellular carcinoma