ĐẶC ĐIỂM HÌNH ẢNH VÀ KẾT QUẢ ĐIỀU TRỊ NÚT MẠCH HÓA CHẤT UNG THƯ BIỂU MÔ TẾ BÀO GAN Ở BỆNH NHÂN DƯỚI 40 TUỔI

SUMMARY

Objectives: Describe the characteristics of ultrasound images, computed tomography, angiography and results of chemoembolization in patients with HCC under 40 years old at the Radiology Center of Bach Mai Hospital.

Methods: A cross-sectional study was carried out on 25 patients with a confirmed HCC who treated chemoembolization at the Radiology Center - Bach Mai Hospital from August 2018 to August 2021.

Results: On 2-dimensional ultrasound, the majority of HCC tumors had hypoechoic and mixed sound images (72%) and increased angiogenesis on color Doppler ultrasound, reaching 68.0%. On computed tomography images, tumor density decreased 64% and increased angiogenesis 68.0%. Tumors of HCC have increased angiogenesis on angiography, reaching 92%. After treatment AFP tends to decrease in the first 6 months, then increase in the 9th month. Bilirubin tends to decrease in the first 3 months, then increase at 6 and 9 months. Tumor size tends to decrease at 1, 3 and increase at 6, 9 months. Median survival was 13 months with interquartile range [5.5 ÷ 22], the longest survival time with continued follow-up was 57 months.

Conclusion: Chemoembolization therapy is effective in reducing tumor size, bilirubin, AFP and prolonging survival time for patients under 40 years old with HCC.

Keywords: chemoembolization therapy, hepatocellular carcinoma