Nhân một trường hợp ung thư tế bào vảy phổi di căn xương sọ

Skull metastasis arising from pulmonary squamous cell carcinoma: A case report

SUMMARY

Introduction: Squamous cell carcinoma of the lung represents 30% of all non-small cell lung carcinomas. It arises from dysplasia of squamous epithelium of the bronchi and is strongly associated with cigarette smoking. Squamous cell carcinoma of the lung is known to produce metastases in the brain parenchyma.

Case presentation: We present the case of a 77-year-old woman with an unusual presentation of metastatic carcinoma of the lung. The case demonstrated a squamous cell carcinoma of the lung with an intracranial metastatic lesion destroying the parietal bone and extending into the extra cranial soft tissue. A visible deformity as a result of the metastasis was evident on physical examination, magnetic resonance imaging and computed tomography demonstrated extensive bone destruction.

Conclusion: Squamous cell carcinoma of the lung with an intracranial metastatic lesion is rare in the world literature. The case report demonstrates an unusual disease presentation with an intra-cranial metastasis invading through the skull.

Keywords: Destruction of bone; Metastasis; Squamous cell carcinoma.