Xạ hình SPECT 99mTc-MDP phát hiện hạch trung thất và đánh giá đáp ứng với xạ trị ở bệnh nhân ung thư phổi không tế bào nhỏ

The role of 99mTc - MIBI SPECT in the identification of mediastinal lymph node and assesstment of radiotherapeutic response in patients with non-small cell lung cancer

SUMMARY:

36 patients with non-small cell lung cancer underwent a 99mTc-MIBI SPECT studies before starting and after radiotherapy 4 weeks. For neoplastic lung lesions, the diagnostic sensitivity of MIBI SPECT were 100% (36/36 patients). Tumor size on SPECT 5,9 ± 2,5cm, was higher compared 5,6 ± 2,2 cm on CT. For mediastinal lymph node, MIBI SPECT identified 83 lesions in 35 patients, when CT showed only 42 lymph node in 29 patients. 99mTc-MIBI SPECT imaging may be useful to differentiate between necrotic tumor tissue and residual, recurrent lung lesions after radiotherapy.

Key words: 99mTc-MIBI SPECT scan, non-small cell lung cancer.