Ứng dụng sinh thiết( ST) lõi trong chẩn đoán ung thư (UT) gan dưới hướng dẫn siêu âm

Core biopsies for focal hepatic lesions by ultrasound guidance

SUMMARY:

All percutaneous US-guided biopsies for focal liver lesions performed in 37 patients. Among the 54 lesions for which the 18- gauge cutting needle was used, core biopsy was performed once in 23 lesions (62.2%), twice in 11 lesions (29.7%), and three times in 3 lesions (8.1%). The length of tissue cores was above 1cm in 44 lesions (81.5%). Three of the 54 specimens (5.6%) fragmented when placed in formalin. The common complications were 2.7%. No major complications were observed. The core biopsy specimen was sufficient for diagnosis in 36 patients (97.3%) and was insufficient in one. Histologic examination revealed various types of H.C.C (62.2%), peripherial cholangiocarcinoma (2.7%), secondary malignant tumors (8.1%), benign tumors (24.3%). There was high concordance between the histologic and cytologic results (Kappa = 0.579, p < 0.05); and very high concordance between the core biopsy and post surgery histologic results (Kappa = 0.942, p < 0.05).

Key words: core biopsy, focal hepatic lesions, HCC, cholangiocarcinoma.