Nghiên cứu đặc điểm tổn thương trên xạ hình SPECT tưới máu cơ tim ở bệnh nhân sau nhồi máu cơ tim

Characteristics of myocardial perfusion on SPECT at the post - infarct affection

SUMMARY:

Aims: the purpose of our study was to evaluate characteristics of myocardial perfusion defects in Tc99msestamibi gated SPECT myocardial perfusion imaging (MPI).

Subjects and methods: 119 post-myocardial infarction (MI) patients were underwent gated SPECT in Nuclear Medicine Department, 108 Central Military Hosspital from March 2007 to May 2010.

Results: in gated SPECT MPI, reversible, mixed and fixed perfusion defects were detected in 63.9%, 18.5% and 17.6%, respectively. In patient group with ESV ≥ 70 ml, SSS and SRS were significantly higher in group with ESV < 70 ml (18.63 ± 5.02 and 15.58 ± 4.99 vs 14.49 ± 4.83 and 11.15 ± 4.63 (p<0,001). There were significant correlations between SRS and SSS with WMS (r = 0.68, p<0.001 and r = 0.61, p<0.001). In patient group with EF ≤ 40%, SSS and SRS were significantly higher in patients with ESV>40% (19.83 ± 4.36 and 17.07 ± 4.58 vs 15.50 ± 5.2 và 12.13 ± 4.85; p<0.001). There were correlation between SRS and SSS with EF (r = - 0.47, p < 0.001) và SSS (r = -0.44, p<0.001).

Conclusions: In post-MI patients, fixed, reversible and mixed defects are frequently detected in SPECT MPI. The extent and severity of perfusion defects are significantly correlated with wall motion, left ventricular volume and ejection fraction evaluated by gated SPECT MPI.