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Imaging characteristics on and value MRI of myocardial viability in patients with chronic ischemic heart disease

summary

Purposes: 1. To describe the imaging characteristics on CMR of myocardial viability in patients with chronic ischemic heart disease; 2. To define the relationship between myocardial viability on magnetic resonance imaging (MRI) with the stenosis degree of coronary artery on invasive coronary angiography (IVA).

Materials and Methods: 37 patients with chronic ischemic heart disease were enrolled in this cross-sectional prospective study. All patients were performed cardiac MRI and IVA during a period from 12/2011 to 8/2012 at Bach Mai Hospital. The data analysis by using the SPSS 18.0 (Chicago, United States).

Results: 37 patients/ 27 males (73%) with mean age: 60.11 ± 11.74 year (35 - 81). Mean left ventricular systolic function (EF): 45.83 ± 12.83% (ranged 16.6 - 72%). 64.9% had EF decreased moderate to severe. 73% had reduction of ventricular contraction. 35 patients (94.6%) had late enhancement, of which 67.6% segments supplied by LAD, 64.8% had extent myocardial scar > 50%. Sensitivity and specificity of late enhancement at coronary artery stenosis ≥ 50% were 97.1%, 33.3% respectively.

Conclusion: The extent of myocardial scar had good relationship with the stenosis degree of coronary artery.

Key word: Cardiac MRI, Chronic ischemic disease, coronary artery.