Nghiên cứu đặc điểm hình ảnh và giá trị chẩn đoán của cộng hưởng từ đối với u nguyên bào thần kinh đệm hai bán cầu

Study of imaging characteristic and value of MRI in diagnosis of hemisphere glioblastoma

SUMMARY:

Purpose: Describing imaging characteristic and assessing the MRI value in the diagnosis of hemisphere glioblastoma.

Materials and methods: 2505 patients of brain tumors were selected in retrospective describe study, diagnosed, operated and having histopathological result from January 2009 to March 2011 in Viet Duc Hospital, in which 45 patients were histologically confirmed of glioblastoma. Based on gold standard of histopathology, the value of MRI in diagnosis of hemisphere glioblastoma was assessed.

Results: Mean age 51±16. Gender: M/F 1.3/1. Location at frontal lobe (26.4%), fronto -temporal lobe (20%), less frequently at occipital lobe. Average diameter more than 5cm (60.4%). Hyposignal on T1W (66%), hypersignal on T2W (70%), marked and heterogenous enhancement (43.4%), rim enhancement (47.3), necrosis (95.6%), cyst component (52.8%), hemorrhage (28.4%); surrounding edema of grade II and III (90%), meningeal and copus callosum invasion (47.2% and 39.6%, respectively). Accurate diagnosis of tumor location was 100% comparing to surgery. Se, Sp and Acc respectively 81.1%, 97.6%, and 98%.

Conclusion: MRI had high value in diagnosis of hemisphere glioblastoma.