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Value of 2 detectors computed tomography in diagnosis o f hepatoblastoma

SUMMARY

Purpose: to evaluate the diagnostic value of 2 detector CT in pediatrichepatoblastoma (HB).

Materials and methods: 69 patients 0-15 year old with clinical diagnosis of liver tumor, had 2 detectors CT-Scaner result of hepatoblastoma or not, all of them had pathology results, from 1/2010 to 5/2014 in National Hospital of Pediatric.

Result: these is no single characteristic of HB on CT-Scaner wich had high value in diagnosis of HB. The characteristic of calcification within the tumor had highest specificity of 90% but with low sensitivity of 34.7%. The value of diagnosis that combine the characteristic of solid tumor on computedtomography with the age under 3 year old has specificity of 55%, sensitivity of 85.7%, when combining the characteristic of solid tumor on computedtomography, age under 3 year old and AFP higher than normal limit has specificity of 80%, sensitivity of 85.7%. CT- Scaner had high value in evaluating the tumor location with very high Kappa score of 0.856 and high in staging PRETEXT of 0.65.

Conclusion: the diagnosis of HB should combine the characteristic of CT- Scaner with the age and value of alfa fetoprotein, wich had high sensitivity and high specificity. CT-Scaner had high value in evaluating tumor location, staging PRETEXT, and infiltration of tumors.

Keywords: hepatoblastoma, liver tumors in children, liver mass in children, hepatoblastoma imaging.