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Evaluating results and side effects of rotating gamma knife radiosurgery in the treatment of cavernoma on the tentorium cerebellum at bach mai hospital

SUMMARY

Aim: Evaluating results and side effects of rotating gamma knife radiosurgery in the treatment of cavernoma on the tentorium cerebellum at Bach Mai hospital.

Patients and Method: Retrospective study of 81 patients with cavernoma on the tentorium cerebellum at Bach Mai hospital from July 2008 đến May 2015.

Results: 35.8 % of patients 30-40 years of age (the youngest was 8, the oldest was 79 years old), male/female ≈ 1/1. Tumors located in the temporal lobe (40.7%), frontal lobe (25.9%), location deep in the brain (11.2%). 97.6% tumors side £ 3 cm, including 58.8% from 10 to 19 mm. The average dose radiosurgery was 18.7 ± 2.8 (Gy).

Effective treatment: Patients’ symptoms were improved with time, 75% of patients had decreased or ended headache, 78.1% of patients were reduced or stopped convulsing 6 months after radiosurgery. Tumor size was decreased with time, response to treatment according to tumor size: 42% partial response, 54.6% stable disease, three patients had progressive disease. Side effects of rotating gamma knife after radiosurgery were mostly mild and acceptable. Conclusion: Gamma knife radiosurgery for patient with cavernoma on the tentorium cerebellum is a effective and safe treatment methods for both adult and pediatric patients.

Keywords: gamma knife radiosurgery, cavernoma.