NGHIÊN CỨU ĐẶC ĐIỂM XẠ HÌNH XƯƠNG VỚI 99mTc-MDP TRONG BỆNH U NGUYÊN BÀO THẦN KINH TẠI BỆNH VIỆN NHI TRUNG ƯƠNG TỪ THÁNG 1/2018 - 03/2020

SUMMARY

Objective: To determine the proportion of bone metastasis and whole-body scintigraphy with 99mTc-MDP in neuroblastoma (NB) in children.

Subjects and Methods: A retrospective descriptive combined prospective study was conducted on 86 patients under 15 years old, diagnosed with NB according to the standards of Pediatric Oncologists Conference in 1988 and had whole-body scintigraphy with 99mTc-MDP at Vietnam National Children's Hospitalfrom January 2018 to March 2020.

Results: The proportion of detection metastasis was 33.7%. There are 55.2% patients with bone metastases without clinical manifestations (without bone pain). 100% cases of bone metastases on whole-body scintigraphy have images of increased radioactivity. Most of the patients were about 2 - 4 years old 58.6%, lower limb position 62.1%, multifocal lesions 72.4%, of which 58.6% patients had over 5 lesions.

Conclusions: Whole-body scintigraphy with 99mTc-MDP is a valuable technique for detecting bone metastases on NB in the early stage when absence of clinical manifestations of bone metastases.

Keywords: Neuroblastoma, whole-body scintigraphy, 99mTc-MDP.