BƯỚC ĐẦU NGHIÊN CỨU ĐẶC ĐIỂM HÌNH ẢNH VÀ VAI TRÒ CỦA 18FDG-PET/CT TRONG CHẨN ĐOÁN GIAI ĐOẠN UNG THƯ ĐẠI TRỰC TRÀNG TRƯỚC ĐIỀU TRỊ

SUMMARY

Objectives: To evaluate the imaging characteristics and the role of 18FDG-PET/CT in pre-treatment colorectal cancer staging.

Subjects and methods: Study on 39 colorectal cancer patients without specific treatment who had taken 18FDG-PET/CT for staging diagnosis, at the Department of Nuclear Medicine, Imaging Center of Military Hospital 103, from February 2017 to November 2020.

Results: The average age was 62.77 ± 14.07. The ability to detect primary tumor lesions in the colorectal of 18FDG-PET/CT was 97.44%. The majority of patients had rectal tumors, the tumor size was mainly in the range of 5-10 cm and the T3 stage accounted for the most proportion with 60.5%. There was 46.2% of patients had regional lymph node metastasis, in which the group of lymph nodes over 10 mm and the N2 group accounted for a lower proportion, but the mean SUVmax was statistically significantly higher than others group. Distant metastasis was occured mainly in liver, lung-pleural and bone. There were 59.0% patients in stage III and IV. Diagnosis by 18FDG-PET/CT was accurately at 80.77% for T stage and 66.67% for N stage. The sensitivity and specificity, positive predictive value and negative predictive value of 18FDG-PET/CT in the diagnosis of regional lymph node metastasis were 100% and 60%; 55.55% and 100%.

Keywords: Colorectal cancer, 18FDG-PET/CT, SUVmax.