GIÁ TRỊ CÁC THÔNG SỐ BÁN ĐỊNH LƯỢNG CỦA CỘNG HƯỞNG TỪ ĐỘNG HỌC TRONG CHẨN ĐOÁN PHÂN BIỆT TỔN THƯƠNG VÚ LÀNH TÍNH VÀ ÁC TÍNH

SUMMARY

Objective: The aims of this study were to determine the value of the semi-quantitative parameters obtained by dynamic contrast enhancement magnetic resonance imaging (DCE-MRI) in differentiation between benign and malignant breast lesions.

Methods: A retrospective study was performed on 63 females (with 72 breast lesions) underwent DCE-MRI before treatment at Cho Ray hospital from Jan 2019 to Feb 2020. The value of semi-quantitative parameters (signal intensity slope (SIslope), maximum slope of increase (MSI), percentage of peak enhancement (Epeak)) were evaluated. The diagnostic value of the time intensity curve according to 5th edition ACR (2013) was compared with the value based on semi-quantitative methods. The results of each DCE-MRI parameter were correlated with histopathology.

Results: There were 63 patients with 72 breast lesions including 40 benign lesions and 32 malignant lesions. The area under the ROC curve of SIslope, MSI and Epeak were 0,908; 0,702 and 0,734, respectively. The sensitivity, specificity and accuracy of the time intensity curve according to ACR and semi-quantitative methods were 68,8% and 87,5%; 87,5% and 85%; 79,2% and 86,1%, respectively.

Conclusion: Our study reinforces the importance of the semi-quantitative parameters of DCE-MRI in distinguishing between benign and malignant breast lesions. Semi-quantitative analysis of the time intensity curve helps to increase the diagnostic accuracy compared with the methods of ACR.

Key words: breast lesions; semi-quantitative parameters; time intensity curve.