Nghiên cứu ứng dụng kĩ thuật sinh thiết lõi qua thành ngực dưới hướng dẫn của siêu âm

Ultrasound-guided transthoracic core biopsy

SUMMARY:

Background: On the global scale, primary lung cancer is a major contributor to both cancer incidence and mortality. Definite diagnosis can be made from cytology or biopsy . A variety of techniques are available and helpful for the sampling include bronchoscopy, fine needle aspiration or image-guided biopsy, in which ultrasound-guided core biopsy of lung solid masses has been widely used as it is available, convenient and cost-effective.

Material and method: A cross-sectional study was done on a sample of 77 individuals who had juxtapleural lung solid masses detected by Ultrasound or CT scan at Hue central hospital, from January-2010 to August-2011. All of these have undergone ultrasound-guided core biopsy. Objectives were to evaluate the efficacy, advantages and disadvantages of the technique.

Results: The successful rate of single sampling was 89.6%. Five patients had twice sampling which raised the successful rate up to 94.8%, from which 89.6% were indicated malignant and the rest 5.2% were benign lesions. Advantages were multiple sampling (>2), supine and inclination position, skin surface-lesion distance less than 3 cm, pleura-lesion interface over 2 cm, lesion’s depth over 2 cm. Disadvantages include multiple sampling, lesion’s depth over 3 cm, FEV1/FVC < 0.7, needle size (<17G), prolonged procedure (>25 minutes). Rate of complication was 14.6%, in which pneumothorax was the most likely (4.9%), but no pleural drainage needed.

Conclusion: ultrasound-guided core biopsy appeared safe, effective, non radiation exposure, cost-saving, simple and applicable in clinical setting.

Key words: ultrasound-guided biopsy, lung solid mass.